Overview of Chosen Chemical Compounds and Intermediates

Overview of Chosen Chemical Compounds and Intermediates

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one. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This is certainly an impurity connected with bortezomib, a proteasome inhibitor Utilized in the remedy of a number of myeloma. Its synthesis or research is essential for making sure the purity and security of the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor during the synthesis of abiraterone acetate, a drug Utilized in the therapy of prostate most cancers by inhibiting androgen output.
Imatinib Intermediate (CAS NO. 152460-10-one): A crucial compound during the synthesis of imatinib, a drug that targets distinct varieties of most cancers, like Persistent myelogenous leukemia (CML).
Docetaxel Intermediate: A compound Utilized in the synthesis of docetaxel, a chemotherapy medication that treats many cancers for instance breast, lung, and prostate cancer.
two. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, eight): These are definitely intermediates inside the synthesis of gemcitabine, an anti-most cancers drug. Their examine is significant for optimizing the creation method and guaranteeing substantial purity.
Lapatinib Intermediate (CAS NO. 231278-84-five): Lapatinib is used to deal with breast cancer, and these intermediates are involved with its output.
Fulvestrant Intermediates: Fulvestrant can be an estrogen receptor antagonist used in the procedure of breast most cancers. Various intermediates assist in the synthesis of this TBTU drug.
Paclitaxel Side Chain Acid (CAS NO. 949023-16-9): This intermediate is Utilized in the synthesis of paclitaxel, a chemotherapy drug productive in dealing with cancers including ovarian, breast, and lung most cancers.
three. Other Noteworthy Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-three): A chemotherapy drug Employed in the treatment of colorectal cancer and modest mobile lung most cancers.
3-Amino-1-hydroxyadamantane (CAS 702-82-9): This compound is involved with the synthesis of adamantane derivatives, that have several purposes, such CAS 702-82-9 as antiviral Qualities.
Vildagliptin Intermediates: Utilized in the manufacture of vildagliptin, an oral drug for variety 2 diabetes that inhibits the enzyme DPP-4 to regulate blood sugar ranges.
4. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-forty eight-one): This compound is involved with the synthesis of varied gluconic acid derivatives, which might be Utilized in foods, pharmaceutical, and industrial applications.
Canagliflozin Intermediate two: A precursor during the synthesis of canagliflozin, a medication used to deal with style two diabetes by inhibiting sodium-glucose co-transporter 2 (SGLT2).